ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Panduragan Baskaran, Balaji Bathrinarayanan, Rajasekar Perumal, Syed Sheik Mansoor

Email(s): mansoorcah@gmail.com

DOI: 10.52711/0974-4150.2023.00072   

Address: Panduragan Baskaran, Balaji Bathrinarayanan, Rajasekar Perumal, Syed Sheik Mansoor*
Research Department of Chemistry, Bioactive Organic Molecule Synthetic Unit,
C. Abdul Hakeem College (Autonomous), Melvisharam – 632509,
Affiliated to Thiruvalluvar University, Vellore, Tamil Nadu, India.
*Corresponding Author

Published In:   Volume - 16,      Issue - 6,     Year - 2023


ABSTRACT:
An efficient procedure for the synthesis of various 2-amino-3-cyano-6-methyl-4-aryl-4H-pyrans is reported. It has been found that Caffeine catalyse the condensation reaction of aromatic aldehydes, malononitrile and ethyl acetoacetate efficiently under EtOH-H2O (1:1) at reflux conditions. This approach provides many merits such as high yields of products, clean, simple work-up, waste free, mild reaction conditions and commercially available catalyst.


Cite this article:
Panduragan Baskaran, Balaji Bathrinarayanan, Rajasekar Perumal, Syed Sheik Mansoor. Caffeine: An efficient and Reusable catalyst for the multicomponent synthesis of 2-amino-3-cyano-6-methyl-4-aryl-4H-pyrans. Asian Journal of Research in Chemistry. 2023; 16(6):438-2. doi: 10.52711/0974-4150.2023.00072

Cite(Electronic):
Panduragan Baskaran, Balaji Bathrinarayanan, Rajasekar Perumal, Syed Sheik Mansoor. Caffeine: An efficient and Reusable catalyst for the multicomponent synthesis of 2-amino-3-cyano-6-methyl-4-aryl-4H-pyrans. Asian Journal of Research in Chemistry. 2023; 16(6):438-2. doi: 10.52711/0974-4150.2023.00072   Available on: https://www.ajrconline.org/AbstractView.aspx?PID=2023-16-6-8


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