Author(s):
Kajal Patel, Poonam Maurya, Rohit Tripathi, Arvind Kumar Srivastava, Mandvi Tiwari
Email(s):
mandvi.s108@gmail.com
DOI:
10.52711/0974-4150.2026.00001 
Address:
Kajal Patel1, Poonam Maurya2, Rohit Tripathi3, Arvind Kumar Srivastava3, Mandvi Tiwari1*
1Department of Pharmacology, Shambhunath Institute of Pharmacy, Prayagraj, U.P., India - 211015.
2Department of Pharmaceutics, Shambhunath Institute of Pharmacy, Prayagraj, U.P., India - 211015.
3Department of Pharmaceutical Chemistry, Shambhunath Institute of Pharmacy, Prayagraj, U.P., India - 211015.
*Corresponding Author
Published In:
Volume - 19,
Issue - 1,
Year - 2026
ABSTRACT:
Anxiety illness is one of the most prevalent mental health conditions. In the past ten years it currently affects one eight of the world’s population and has become a prominent area of study in psychopharmacology. Rubia cordifolia, which commonly known as Indian madder it is also known as manjistha one of the most common medicinal plants that belong to the Rubaceae family is manly found in Asia, Greece, and Africa and is prized for its high concentration of bioactive compounds. Rubia cordifolia, an ayurvedic herb is a perennial climber with very long cylindric flexible root and thin red bark long and grouped in four whorls, oval sharp bottom leaves. This study used aqueous leaf extract to assess its anxiolytic (anti-anxiety) properties. In this research article, the rats were given dosages of 100 and 200mg/kg Rubia cordifolia aqueous leaf extract for 28 days, and mCPP was used to create anxiety. It was found that the rats significantly spent more time in open and bright areas during behavioral tests (elevated plus maze and light-dark box), which suggested a decrease in anxiety. Flavonoids, alkaloids, tannins, and phenolic substances were detected via phytochemical examination. The strongest anxiolytic effect was observed at a dosage of 200mg/kg.
Cite this article:
Kajal Patel, Poonam Maurya, Rohit Tripathi, Arvind Kumar Srivastava, Mandvi Tiwari. Evaluation of Antianxiety Activity of Aqueous Leaves Extract of Rubia cordifolia on Rats. Asian Journal of Research in Chemistry. 2026; 19(1):1-5. doi: 10.52711/0974-4150.2026.00001
Cite(Electronic):
Kajal Patel, Poonam Maurya, Rohit Tripathi, Arvind Kumar Srivastava, Mandvi Tiwari. Evaluation of Antianxiety Activity of Aqueous Leaves Extract of Rubia cordifolia on Rats. Asian Journal of Research in Chemistry. 2026; 19(1):1-5. doi: 10.52711/0974-4150.2026.00001 Available on: https://www.ajrconline.org/AbstractView.aspx?PID=2026-19-1-1
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