Synthesis of Novel Substituted 3,4-Dihydroquinoxaline Derivatives as Antimicrobial Agents

Charoo S. Garg; Jimit S. Patel; Dhrubo Jyoti Sen

Asian Journal of Research in Chemistry

ISSN

0974-4150 (Online)
0974-4169 (Print)

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Synthesis of Novel Substituted 3,4-Dihydroquinoxaline Derivatives as Antimicrobial Agents

Author(s): Charoo S. Garg, Jimit S. Patel, Dhrubo Jyoti Sen

Email(s): charoo23pharma@gmail.com

DOI: Not Available

Address: Charoo S. Garg*, Jimit S. Patel and Dhrubo Jyoti Sen
Department of Pharmaceutical Chemistry, Shri Sarvajanik Pharmacy College, Gujarat Technological University, Arvind Baug, Mehsana-384001, Gujarat
*Corresponding Author

Published In: Volume - 5, Issue - 7, Year - 2012

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ABSTRACT:
As a part of research project on the synthesis of number of substituted quinoxaline derivatives with electron donating as well as electron withdrawing groups has been done and evaluated them for antibacterial and antifungal activity. First of all different acetanilides were prepared by taking chloro acetyl chloride and substituted anilines. Then they were condensed with benzene diamine to form novel quinoxaline derivatives. Further quinoxalines were benzoylated by using 4-methoxy benzoyl chloride and 4-chloro benzoyl chloride. The purity of all compounds have been checked by the TLC monitoring and the confirmation of the structure was checked by different spectral analysis like UV, IR, Mass and NMR and evaluated for antibacterial agent using ciprofloxacin as a standard drug and for antifungal activity using clotrimazole as a standard drug.

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Cite this article:
Charoo S. Garg, Jimit S. Patel, Dhrubo Jyoti Sen. Synthesis of Novel Substituted 3,4-Dihydroquinoxaline Derivatives as Antimicrobial Agents. Asian J. Research Chem. 5(7): July, 2012; Page 819-826.

Cite(Electronic):
Charoo S. Garg, Jimit S. Patel, Dhrubo Jyoti Sen. Synthesis of Novel Substituted 3,4-Dihydroquinoxaline Derivatives as Antimicrobial Agents. Asian J. Research Chem. 5(7): July, 2012; Page 819-826. Available on: https://www.ajrconline.org/AbstractView.aspx?PID=2012-5-7-2

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Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

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Asian Journal of Research in Chemistry

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