ABSTRACT:
In this present study, p-amino acetophenone condensed with p-nitro benzaldehyde in ethanolic solution of sodium hydroxide to yield corresponding chalcone, which reacts with various aromatic aldehydes in glacial acetic acid to yield corresponding Schiff bases. These chalcones were further reacted with urea, thiourea, guanedin in the presence of base in ethanol, which led to the formation of pyrimidine derivatives. Thin layer chromatography was used to follow the reactions. All the compounds have been characterized by FT-IR Spectroscopy, some of them characterized by (1H -NMR)-spectra and elemental analysis (C.H.N).
Cite this article:
Hanan Falih Mohsin. Synthesis of some New Pyrimidines from Chalcone Containing an Imin Group. Asian J. Research Chem. 6(9): September 2013; Page 849-854.
Cite(Electronic):
Hanan Falih Mohsin. Synthesis of some New Pyrimidines from Chalcone Containing an Imin Group. Asian J. Research Chem. 6(9): September 2013; Page 849-854. Available on: https://www.ajrconline.org/AbstractView.aspx?PID=2013-6-9-11