Asian Journal of Research in Chemistry

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0974-4150 (Online)
0974-4169 (Print)


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Synthesis of Some Novel Chalcone containing Pyrazole Moiety

Author(s): V. A. Modhavadiya

Email(s): drvasta20@gmail.com

DOI: 10.5958/0974-4150.2018.00031.7   

Address: V. A. Modhavadiya
Department of Chemistry, Shree M. M. Science college, Morbi-363642
Saurashtra University, Rajkot, Gujarat India
*Corresponding Author

Published In:   Volume - 11,      Issue - 1,     Year - 2018

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ABSTRACT:
Compounds having the sulphonamide group has long been used as drugs for various diseases. The biological activity of these drugs is enhanced by complexation with metal ions. Transition metal Fe (II) complex of ligand derived from sulfamethizole and substituted p-cresol have been prepared and evaluated for antimicrobial activity. The products have been characterized by elemental analysis, IR, NMR, UV-Vis spectral studies, conductivity measurements, magnetic susceptibility measurements, molecular weight determination and stepwise stability constants by PH metric method. The elemental analysis revealed that the azo dye ligand coordinated to the metal ions in 1:2 (metal-ligand) molar ratios. The complex are non-electrolytes as confirmed by their conductivity measurements. The infrared data indicates that the ligand are coordinated with meal ions through diazo (-N=N-) nitrogen and phenolic (-OH) oxygen. The spectral data suggest distorted octahedral geometry as shown in the proposed structure.


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Cite this article:
V. A. Modhavadiya. Synthesis of Some Novel Chalcone containing Pyrazole Moiety. Asian J. Research Chem. 2018; 11(1):149-152. doi: 10.5958/0974-4150.2018.00031.7

Cite(Electronic):
V. A. Modhavadiya. Synthesis of Some Novel Chalcone containing Pyrazole Moiety. Asian J. Research Chem. 2018; 11(1):149-152. doi: 10.5958/0974-4150.2018.00031.7   Available on: https://www.ajrconline.org/AbstractView.aspx?PID=2018-11-1-31


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Asian Journal of Research in Chemistry (AJRC) (ISSN: print-0974-4169, Online-0974-4150) is an international, peer-reviewed journal devoted to pure and applied chemistry. AJRC publishes Original Research Articles, Short Communications, Review Articles in all aspects of chemistry. Topics covered including the traditional areas of analytical, inorganic, organic, biochemistry, forensic, physical-theoretical chemistry as well as newer interdisciplinary areas such as agriculture, materials science, computational, medicine, spectroscopy, polymers, supramolecular, surface, chemical physics, biological, medicinal/ drugs, environmental and pharmaceutical chemistry.
The journal is published quarterly every year in last week of March, June, September and December. From January 2011, is monthly and shall be published every year in last week of Month.    
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