Asian Journal of Research in Chemistry

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0974-4150 (Online)
0974-4169 (Print)


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Synthesis and Antibacterial Study of Some New Schiff's Bases of 2-Hydrazinyl-1-(1H-Imidazole-1-yl)-Ethanone

Author(s): Ravi N. Patel, Urviben Yashodharabhai Patel, Ripal R. Chaudhari, Dhrubo Jyoti Sen

Email(s): dhrubosen69@yahoo.com , ripalchaudhari@yahoo.com

DOI: Not Available

Address: Ravi N. Patel, Urviben Yashodharabhai Patel, Ripal R. Chaudhari and Dhrubo Jyoti Sen
Department of Pharmaceutical Chemistry, Shri Sarvajanik Pharmacy College, Hemchandracharya North Gujarat University, Arvind Baug, Mehsana-384001, Gujarat, India
*Corresponding Author

Published In:   Volume - 4,      Issue - 1,     Year - 2011

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ABSTRACT:
Imidazole on reaction with chloroacetyl chloride afford 2-chloro-1-(1H-imidazole-1-yl)-ethanone, 1 which on treatment with hydrazine hydrate has yielded 2-hydrazinyl-1-(1H-imidazol-1-yl)-ethanone, 2. Condensation of 2 with various aromatic aldehydes afforded sustituted Schiff’s base of 2-hydrazinyl-1-(1H-imidazol-1-yl)-ethanone. The structures of all the products were characterized on the basis of their IR, Mass and 1H-NMR spectroscopic data analysis. All the synthesised products were screened for their antibacterial activity against gram-positive and gram-negative bacteria by cup-plate method.


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Cite this article:
Ravi N. Patel, Urviben Yashodharabhai Patel, Ripal R. Chaudhari, Dhrubo Jyoti Sen. Synthesis and Antibacterial Study of Some New Schiff's Bases of 2-Hydrazinyl-1-(1H-Imidazole-1-yl)-Ethanone. Asian J. Research Chem. 4(1): January 2011; Page 55-57.

Cite(Electronic):
Ravi N. Patel, Urviben Yashodharabhai Patel, Ripal R. Chaudhari, Dhrubo Jyoti Sen. Synthesis and Antibacterial Study of Some New Schiff's Bases of 2-Hydrazinyl-1-(1H-Imidazole-1-yl)-Ethanone. Asian J. Research Chem. 4(1): January 2011; Page 55-57.   Available on: https://www.ajrconline.org/AbstractView.aspx?PID=2011-4-1-10


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Asian Journal of Research in Chemistry (AJRC) (ISSN: print-0974-4169, Online-0974-4150) is an international, peer-reviewed journal devoted to pure and applied chemistry. AJRC publishes Original Research Articles, Short Communications, Review Articles in all aspects of chemistry. Topics covered including the traditional areas of analytical, inorganic, organic, biochemistry, forensic, physical-theoretical chemistry as well as newer interdisciplinary areas such as agriculture, materials science, computational, medicine, spectroscopy, polymers, supramolecular, surface, chemical physics, biological, medicinal/ drugs, environmental and pharmaceutical chemistry.
The journal is published quarterly every year in last week of March, June, September and December. From January 2011, is monthly and shall be published every year in last week of Month.    
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