ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Naresh M. Kalsariya, R.M. Chodavadia, P.B. Patel, Z.N. Mevada, B.P. Marolia, S.A. Shah

Email(s): kalsariya_naresh@yahoo.com

DOI: Not Available

Address: Naresh M. Kalsariya*, R.M. Chodavadia, P.B. Patel, Z.N. Mevada, B.P. Marolia and S.A. Shah
Department of Quality Assurance, Maliba Pharmacy College, Bardoli-Mahuva Road, Tarsadi, Dist. Surat, Gujarat, India- 394 350
*Corresponding Author

Published In:   Volume - 4,      Issue - 12,     Year - 2011


ABSTRACT:
Two spectroscopic methods for simultaneous estimation of cefpodoxime proxetil (CP) and ofloxacin (OFL) in combined tablet dosage form have been developed. The first method is simultaneous equations method which involves the formation of simultaneous equations at 234.90 nm (?max of cefpodoxime) and 298 nm (?max of ofloxacin). The second method is Q-analysis method (Q-absorbance ratio), which involves the formation of Q-absorbance equation at 271.60 nm (Iso-absorptive point) and 298 nm (?max of ofloxacin). In this both method the linearity was evaluated over the concentration range of 2-10µg/ml for cefpodoxime and ofloxacin. The accuracy of the methods were assessed by recovery studies and was found to be 100.9±0.16% and 98.22±0.44% for simultaneous equations method and 99.5±0.133% and 98.90±0.65% for Q-absorbance ratio method for cefpodoxime and ofloxacin respectively. The proposed methods are simple, accurate, precise, rapid and cost effective. Therefore the proposed methods can be used for routine analysis of both drugs in bulk as well as in pharmaceutical formulations.


Cite this article:
Naresh M. Kalsariya, R.M. Chodavadia, P.B. Patel, Z.N. Mevada, B.P. Marolia, S.A. Shah. Simultaneous Estimation of Cefpodoxime Proxetil and Ofloxacin in Combined Dosage Form by UV-Spectrophotometric Method. Asian J. Research Chem. 4(12): Dec., 2011; Page 1836-1839.

Cite(Electronic):
Naresh M. Kalsariya, R.M. Chodavadia, P.B. Patel, Z.N. Mevada, B.P. Marolia, S.A. Shah. Simultaneous Estimation of Cefpodoxime Proxetil and Ofloxacin in Combined Dosage Form by UV-Spectrophotometric Method. Asian J. Research Chem. 4(12): Dec., 2011; Page 1836-1839.   Available on: https://www.ajrconline.org/AbstractView.aspx?PID=2011-4-12-7


Recomonded Articles:

Author(s): Ravi N. Patel, Urviben Y. Patel, Kiran M. Patel, Jimit S. Patel, Ankit D. Patel, Dhrubo Jyoti Sen

DOI:         Access: Open Access Read More

Author(s): Chavan Pooja Ajit, Avinash Mahadeo Bhagwat, Atul Prabhakar Chaudhari

DOI: 10.52711/0974-4150.2021.00061         Access: Open Access Read More

Author(s): Y. Padmavathi, Akari Anjali, Nayaka Raghavendra Babu, P Ravi Kumar

DOI: 10.5958/0974-4150.2017.00064.5         Access: Open Access Read More

Author(s): Nachiket S. Dighe, Priyanka R. Varade, Ganesh S. Shinde, Priya S. Rao

DOI: 10.5958/0974-4150.2019.00028.2         Access: Open Access Read More

Author(s): PA Jadhav, CS Raut, JP Bidada, BB Buwa, PN Dhabale, SC Dhawale

DOI:         Access: Open Access Read More

Author(s): Alka Verma, Bhupesh Verma, Sunil Kumar Prajapati, Kishu Tripathi

DOI:         Access: Open Access Read More

Author(s): Vatchavai Bhaskara Raju, Bonthu Mohan Gandhi, Kamatham Srinivas Sumanth, Kolli Srinivas, Tupakula N Venkata Lakshmi Neeraja

DOI: 10.5958/0974-4150.2017.00030.X         Access: Open Access Read More

Author(s): Banerjee S, Bonde CG, Merukar SS, Patil YR

DOI:         Access: Open Access Read More

Author(s): Nikita N. Patel, Charmy S. Kothari

DOI:         Access: Open Access Read More

Author(s): RB Kakde, VH Kotak, DL Kale

DOI:         Access: Open Access Read More

Author(s): Shashi Ravi Suman Rudrangi, Vijaya Kumar Bontha, Venkata Reddy Manda, Srinivas Bethi

DOI:         Access: Open Access Read More

Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0974-4150 

Popular Articles


Recent Articles




Tags