ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Rajan V. Rele

Email(s): drvinraj@gmail.com

DOI: 10.5958/0974-4150.2019.00006.3   

Address: Rajan V. Rele*
Department of Chemistry, D. G. Ruparel College, Mahim, Mumbai 400016.
*Corresponding Author

Published In:   Volume - 12,      Issue - 1,     Year - 2019


ABSTRACT:
A sensitive non-aqueous potentiometric titration method was developed for quantitative determination of secnidazole from pharmaceutical dosage form. The titration was carried out using standardized 0.1 N perchloric acid. The proposed method was found to be precise with % RSD <1 (n = 6). The method showed strict linearity (r2> 0.999) between 20 % to 100 % of 500 mg of drug substance weight. The percentage recovery of secnidazole in the optimized method was between 99.643 to 100.505 %. The method is also found to be rugged when checked by different analysts and using different lots of reagents and different makes of titrators.


Cite this article:
Rajan V. Rele. A non-Aqueous Potentiometric Titration Method for Validation of Secnidazole from Pharmaceutical Dosages. Asian J. Research Chem. 2019; 12(1): 25-28. doi: 10.5958/0974-4150.2019.00006.3

Cite(Electronic):
Rajan V. Rele. A non-Aqueous Potentiometric Titration Method for Validation of Secnidazole from Pharmaceutical Dosages. Asian J. Research Chem. 2019; 12(1): 25-28. doi: 10.5958/0974-4150.2019.00006.3   Available on: https://www.ajrconline.org/AbstractView.aspx?PID=2019-12-1-6


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DOI: 10.5958/0974-4150 

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